Coronavirus

That's pretty sad - though he seems to be handling it exceptionally well...
 

Results

15,124 articles were identified by the search strategy. After eliminating duplicate titles and completing title, abstracts and full-text review, 18 studies were included comprising of 412,957 patients with COVID-19 (46.63 % male) and 411,929 patients without COVID-19 (46.59 % male). The overall mean Montreal Cognitive Assessment (MoCA) score in COVID-19 patients was 23.34 out of 30 (95 % CI [22.24, 24.43]). indicating cognitive impairment. The overall proportion of patients identified as having new onset cognitive impairment was 65 % (95 % CI [44,81]). Subgroup analyses indicated that time since infection significantly improves overall MoCA score and reduces proportion of patients with cognitive impairment.
 

More than a year after COVID-19 hospitalization, many patients have worse cognitive function than those who weren't hospitalized, a symptom that comes with reduced brain volume and brain injury markers on blood tests, according to a new study, the largest of its kind in the United Kingdom.
The multicenter study from the COVID-CNS Consortium included 351 patients who were hospitalized for COVID and 2,927 matched controls. The researchers, led by a team at the University of Liverpool and King's College London, published their findings yesterday in Nature Medicine.

Looking for brain-fog markers​

Study goals included understanding biological causes and long-term outcomes of neurologic and neuropsychiatric complications following COVID hospitalization. Researchers tested participants' cognitive skills and examined findings from brain scans and blood tests 12 to 18 months after hospitalization.
Greta Wood, MBBS, first author of the study and an academic clinical fellow in infectious diseases at the University of Liverpool, said in university press release that many patients hospitalized with COVID report persistent symptoms, often called "brain fog."
"However, it has been unclear as to whether there is objective evidence of cognitive impairment and, if so, is there any biological evidence of brain injury; and most importantly if patients recover over time," she said.

Cognitive deficits resembled 2 decades of aging​

Of the patients hospitalized for COVID, some did and some didn't have new neurologic complications. The researchers found that both groups had worse cognition than expected for their age, sex, and level of education.
One of the most striking findings was that post-COVID deficits in hospitalized patients look similar to 20 years of normal aging. The team also found that people who had been hospitalized with COVID had reduced brain volume in key areas and abnormally high levels of brain injury proteins in their blood.
The team saw the greatest deficits in people who had the most severe infections, had post-acute psychiatric symptoms, and had a history of encephalopathy.
In a promising finding, longer-term follow-up of 106 patients pointed to a trend toward recovery.

Could other severe infections cause similar problems?​

Benedict Michael, MBChB, PhD, the study's corresponding author and professor of neuroscience at the University of Liverpool, said COVID isn't just a lung condition, and some of the most severely affected patients are those who have brain complications.
That the cognitive impairments occurred alongside brain-cell injury markers and reduced brain volume on magnetic resonance imaging suggest there may be measurable biomechanisms, he said. "Now our group is working to understand whether the mechanisms that we have identified in COVID-19 may also be responsible for similar findings in other severe infections, such as influenza."
Gerome Breen, PhD, a study author and psychiatric geneticist with King's College London, said the work might be helpful for guiding similar studies of patients with long COVID who had milder respiratory symptoms who also report brain fog and for the development of treatment strategies.
emphasis mine
 

More than 1,000 new COVID deaths were reported in the U.S. this week, taking the death toll for the past two months to more than 10,000, according to figures collected by BNO News. New cases, however, are dropping nationwide in the aftermath of the summer wave.
3x 911 worth of deaths in the last two months but sure, COVID is over.
 
So one rando got adverse effects from a vaccine and the BBC decided to do a full page spread on it?

It sounds like a lawsuit waiting for Pfizer. He could have made millions if we had a normal life and herd immunity was deployed.
 

What is going to get you first, Grand Potentate Grand Potentate , death from Covid, from Long Covid or from Covid vaccine?
Another one of your horseshit meta-analysis studies. This one is incredibly flawed, and that is before you get to this beauty:

Conflicts of Interest

Drs. Alexander, Amerling, Gessling, Hodkinson, Makis, McCullough, Risch, are affiliated with and receive salary support and/or hold equity positions in The Wellness Company, Boca Raton, FL which had no role in funding, analysis, or publication. Nothing to declare for Dr. Trozzi and Mr. Hulscher.

I happen to live near the area where this clinic is and I can tell you it’s ground zero for anti-vaxers and alternative health nuts. Hell, they even sell a “spike” support related supplement:


And one for kids as well!


Can I interest you in a $325 contagion emergency kit?


Contains all these helpful items:

IMG_1723.webp

Just wait until you see their medical ethics page:


Oh wait…

If you need me to keep going I’m more than happy to. Otherwise you can slink off back into your hole of misinformation and bullshit until you feel like cherry picking another garbage study for me to bat down.
 
If you need me to keep going I’m more than happy to. Otherwise you can slink off back into your hole of misinformation and bullshit until you feel like cherry picking another garbage study for me to bat down.
Please bat down the 44 garbage studies they used for their paper (even more please, which is it then? Covid or Long Covid, I guess?) (also, that's not how you bat down studies, but we can leave that for another time! Keep going while you're on it!)
 
Please bat down the 44 garbage studies they used for their paper (even more please, which is it then? Covid or Long Covid, I guess?) (also, that's not how you bat down studies, but we can leave that for another time! Keep going while you're on it!)
Happily! Lets start with the data at hand. From the abstract:

Data Sources and Search Strategy


We performed a systematic review of all published autopsy and organ-restricted autopsy reports relating to COVID-19 vaccination through May 18th, 2023. We utilized the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA) Statement [18] to limit study selection bias and ensure transparency and completeness in reporting. The following databases were used: PubMed and ScienceDirect. The following keywords were used: “COVID-19 Vaccine,” “SARS-CoV-2 Vaccine,” or “COVID Vaccination,” and “Post-mortem,” or “Autopsy.” All possible keyword combinations were manually searched. The search was not restricted to any language. All selected studies were screened for relevant literature contained in their references.
See if you can find any holes in this methodology.

Next, let move into the Eligibility Criteria section:

Eligibility Criteria and Selection Process


All original articles, randomized clinical trials, case reports, and case series that contain autopsy or organ-restricted autopsy (gross and histologic analysis of a single organ) results with COVID-19 vaccines as an antecedent exposure were included. Review articles, systematic reviews, meta-analyses, papers with no autopsy or organ-restricted autopsy results, non-human studies, and papers with no reported COVID-19 vaccination status were excluded. The authors’ conclusions were not considered for study inclusion to avoid bias. Two authors (NH and PAM) independently screened the full text of all retrieved studies to assess their eligibility for inclusion and removed all ineligible/duplicate studies. Any disagreements for inclusion of an article were resolved by discussion until agreement was reached.

You'll note here that only two authors are responsible for sorting data, discounting for the fact that said authors "conclusions were not considered for inclusion to avoid bias". First, we have (PAM), who is:
Peter A. McCullough
Affiliation: McCullough Foundation, Dallas, TX. The Wellness Company, Boca Raton, FL. Truth for Health Foundation, Tucson, AZ.

Lets look up the McCullough Foundation in Dallas shall we?:


Huh, now that's weird. It seems like there might be an issue with the good Dr.'s scientific methods. Let's investigate:

How We Make A Difference​


  • Investigative Scholarship

    As we learned during the COVID-19 pandemic, our deep-seated fear of deadly infectious disease makes us very susceptible to manipulation by public health officials (often in league with undeclared commercial interests) who invoke emergency power with the purported objective of protecting us. Thus, our fear of infectious disease can be exploited by unscrupulous public officials in the same way our fear of foreign invaders has been used by dictators and tyrants throughout history. To quote James Madison: “The means of defense against foreign danger have been always the instruments of tyranny at home.”
    Learn More
Boy that sure does sound suspicious. Let's look further into this by clicking on the Learn More button:

Investigative Scholarship​


As we learned during the COVID-19 pandemic, our deep-seated fear of deadly infectious disease makes us very susceptible to manipulation by public health officials (often in league with undeclared commercial interests) who invoke emergency power with the purported objective of protecting us. Thus, our fear of infectious disease can be exploited by unscrupulous public officials in the same way our fear of foreign invaders has been used by dictators and tyrants throughout history. To quote James Madison: “The means of defense against foreign danger have been always the instruments of tyranny at home.”

Safeguarding public health and liberty begins with acquiring knowledge of what poses a true threat to public health and being able to distinguish true threats (such as hastily developed and improperly tested medical products) from grossly exaggerated or fabricated threats. Through investigative scholarship, Dr. Peter McCullough and his colleagues ascertained that, while COVID-19 posed little risk to the young, the COVID-19 vaccines posed a considerable risk to the young. The risk of vaccine-induced myocarditis is especially high among young, male athletes.

In this vein, the Foundation performs independent investigations of public health conditions and policies, and how policies can be optimized for the benefit of a healthy and free citizenry (as distinct from special commercial or political interests).

Another key element of investigative scholarship is researching and monitoring the activities of the Bio-Pharmaceutical Complex—an offshoot of the Military-Industrial Complex that President Eisenhower warned the American people about in his Farewell Address of 1961. The Bio-Pharmaceutical Complex is a public-private partnership of government agencies, international foundations, and pharmaceutical companies that may, at any time, endanger our liberties and democratic processes. By investigating and reporting the activities of this Complex, the McCullough Foundation arms the citizenry with the knowledge to guard itself against “the disastrous rise of misplaced power” that we have experienced in recent years.

Boy that kind of sounds like a bunch of anti-vax bullshit to me. But, I could be wrong. Let's go further down this mine shaft into the depths of this hell:

High-Impact, Global Success​


McCullough Protocol​

Sequenced Multidrug Therapy for Early Ambulatory SARS-CoV-2 Infection to Prevent Hospitalization and Death (McCullough PA, Am J Med, Rev Cardiovasc Med 2000). Dissemination and implementation of this breakthrough saved tens of millions of lives and spared over a hundred million hospitalizations for COVID-19.

https://www.imrpress.com/journal/RCM/21/4/10.31083/j.rcm.2020.04.264

Systematic Review of Autopsies​

Systematic Review of Autopsies in Cases of Death after COVID-19 Vaccination, garnered international press and impressive > 250K downloads and reads from the Zenodo European Commission preprint server demonstrating vaccination is the most likely cause of unexplained death after injection.

https://zenodo.org/record/8120771

Base Spike Protein Detoxification​


Clinical Rationale for Base Spike Protein Detoxification after COVID-19 Vaccination, J Assoc Am Physicians and Surgeons, 2023. First protocol designed to assist the body of clearing accumulated SARS-CoV-2 Spike protein from multiple infections or injections of COVID-19 vaccines.

https://zenodo.org/record/8286460
Now that first study discussing how he's personally developed a method to save tens of millions of lives and spared over a hundred million hospitalizations for Covid-19 really sounds swell. Let's take a look:


Abstract

The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness, hospitalizations, and death. The complex and multifaceted pathophysiology of life-threatening COVID-19 illness including viral mediated organ damage, cytokine storm, and thrombosis warrants early interventions to address all components of the devastating illness. In countries where therapeutic nihilism is prevalent, patients endure escalating symptoms and without early treatment can succumb to delayed in-hospital care and death. Prompt early initiation of sequenced multidrug therapy (SMDT) is a widely and currently available solution to stem the tide of hospitalizations and death. A multipronged therapeutic approach includes 1) adjuvant nutraceuticals, 2) combination intracellular anti-infective therapy, 3) inhaled/oral corticosteroids, 4) antiplatelet agents/anticoagulants, 5) supportive care including supplemental oxygen, monitoring, and telemedicine. Randomized trials of individual, novel oral therapies have not delivered tools for physicians to combat the pandemic in practice. No single therapeutic option thus far has been entirely effective and therefore a combination is required at this time. An urgent immediate pivot from single drug to SMDT regimens should be employed as a critical strategy to deal with the large numbers of acute COVID-19 patients with the aim of reducing the intensity and duration of symptoms and avoiding hospitalization and death.

Not peer-reviewed, but lets let that slide for now. This sounds fantastic. Let's dive in further:

fig2.png


Intracellular anti-infectives sure does sound familiar. I wonder where I heard that before? Let's keep going:

fig3.png


Ruh Roh! Looks like we've got some kooky shit going on here. I wonder what the magical drug is that saved tens of million lives is? Let's see:

5. Ivermectin
Ivermectin (IVM) is a broad spectrum anti-parasitic agent
that has been shown to have anti-viral activity against a range
of viruses including recently, SARS-CoV-2 (Heidary and Ghare-
baghi, 2020). This drug is well tolerated, has a high therapeutic
index and proven safety profile with over 3.7 billion treatments,
and has been used alone or combined with either doxycycline or
azithromycin in early clinical studies of patients with COVID-19
(Rahman et al., 2020). There are a number of randomized and
prospective studies and all have shown efficacy in clinical out-
comes at the time of this report (Alam et al., 2020; Chowdhury
et al., 2020; Gorial et al., 2020; Khan et al., 2020; Nunez et al.,
2020). Hence, it is reasonable in patients where HCQ cannot be
used and favipiravir is not available, that IVM (200-600 mcg/kg
[6-36 mg] single oral dose given daily or every other day for 2-
3 administrations) could be the base of SMDT intended to reduce
viral replication early in the course of COVID-19. However, uncer-
tainty remains at this time concerning optimal dosing and schedule
(Schmith et al., 2020). In the ICON study, IVM use in the hospi-
tal was associated with a 48% relative risk reduction in COVID-19
mortality (Rajter et al., 2020). Currently, there are 36 randomized
clinical trials of ivermectin alone or in combination for ambulatory
and hospitalized patients listed on clinicaltrials.gov.

Ah yes, our old friend Ivermectin! Well, I wonder how that turned out?

Let's go back to our good friend Dr. PAM. From the biography on his website:

Biography​


Dr. McCullough is an internist, cardiologist, epidemiologist holding degrees from Baylor University, University of Texas Southwestern Medical School, University of Michigan, and Southern Methodist University. He manages common infectious diseases as well as the cardiovascular complications of both the viral infection and the injuries developing after the COVID-19 vaccine in Dallas TX, USA. Since the outset of the pandemic, Dr. McCullough has been a leader in the medical response to the COVID-19 disaster and has published “Pathophysiological Basis and Rationale for Early Outpatient Treatment of SARS-CoV-2 (COVID-19) Infection” the first synthesis of sequenced multi-drug treatment of ambulatory patients infected with SARS-CoV-2 in the American Journal of Medicine and subsequently updated in Reviews in Cardiovascular Medicine. He has dozens of peer-reviewed publications on the infection and has commented extensively on the medical response to the COVID-19 crisis in The Hill, America Out Loud, and on FOX NEWS Channel. Dr. McCullough testified multiple times in the US Senate, Texas Senate Committee on Health and Human Services, Arizona Senate and House of Representatives, Colorado General Assembly, New Hampshire Senate, Pennsylvania Senate, and South Carolina Senate concerning many aspects of the pandemic response. Dr. McCullough has had years of dedicated academic and clinical efforts in combating the SARS-CoV-2 virus and in doing so, has reviewed thousands of reports, participated in scientific congresses, group discussions, press releases, and has been considered among the world's experts on COVID-19.
Well that's odd. I thought the paper said there were no conflicts of interest. Let's look further:

He manages common infectious diseases as well as the cardiovascular complications of both the viral infection and the injuries developing after the COVID-19 vaccine in Dallas TX, USA.
"cardiovascular complications of both the viral infection and the injuries developing after the COVID-19 vaccine" sure does sound like someone who might have a financial stake in promoting the theory that vaccines cause bodily harm, doesn't it? I mean, probably not to a fruitcake like you, but to most people that might be considered a big ole' red flag.

Now let's go back to the study to look at the other jackoff doing the data collation:


Nicolas Hulscher​

Corresponding Author
Affiliation: University of Michigan School of Public Health, Ann Arbor, MI. McCullough Foundation, Dallas, TX

Email: nichulscher@gmail.com

Wait, this seems odd. He works at the McCullough Foundation, Dallas, TX with the world famous PAM??? That seems like a bit of a conflict but let's, once again, let that slide. I can't seem to find the esteemed researcher Mr. Hulscher on the website faculty. Upon searching, I saw this about half way down on the home page:

Screenshot 2024-11-19 at 5.32.39 PM.webp

Intern Nic Hulscher??? (That's him on the right in the picture by the way. A real paragon of scientifc inquiry judging by the looks of him.) Surely the esteemed researcher Mr. Hulscher can't be one in the same as a lowly intern can it? I wonder what kind of other work he's doing. Let's "continue reading"


Another Ruh-Roh situation brewing here. Let's read on shall we?

So far, I get the impression that the participants sincerely believe that H5N1 is rapidly evolving to achieve high infectiousness and virulence among humans. Most strike me as people of average intelligence and education and lacking Machiavellian guile. They are acquainted with orthodox representations of H5N1 and do not question these representations. At the same time, they too seem to sense that the purported threat of an evolutionary jump from birds to humans still seems remote.

I have to be honest, it sure seems like the good Dr. PAM and trusty sidekick Nic aren't the best sources for accurate investigation into these particular issues. We have a public health professional on the forum. Dropbear Dropbear what's your take on the validity of said study given its authors and their intent? Of course, he's likely another person of average intelligence and education who lacks Machiavellian guile, so who knows if he can be trusted!
 
Happily! Lets start with the data at hand. From the abstract:


See if you can find any holes in this methodology.

Next, let move into the Eligibility Criteria section:



You'll note here that only two authors are responsible for sorting data, discounting for the fact that said authors "conclusions were not considered for inclusion to avoid bias". First, we have (PAM), who is:
Peter A. McCullough
Affiliation: McCullough Foundation, Dallas, TX. The Wellness Company, Boca Raton, FL. Truth for Health Foundation, Tucson, AZ.

Lets look up the McCullough Foundation in Dallas shall we?:


Huh, now that's weird. It seems like there might be an issue with the good Dr.'s scientific methods. Let's investigate:


Boy that sure does sound suspicious. Let's look further into this by clicking on the Learn More button:



Boy that kind of sounds like a bunch of anti-vax bullshit to me. But, I could be wrong. Let's go further down this mine shaft into the depths of this hell:


Now that first study discussing how he's personally developed a method to save tens of millions of lives and spared over a hundred million hospitalizations for Covid-19 really sounds swell. Let's take a look:




Not peer-reviewed, but lets let that slide for now. This sounds fantastic. Let's dive in further:

fig2.png


Intracellular anti-infectives sure does sound familiar. I wonder where I heard that before? Let's keep going:

fig3.png


Ruh Roh! Looks like we've got some kooky shit going on here. I wonder what the magical drug is that saved tens of million lives is? Let's see:



Ah yes, our old friend Ivermectin! Well, I wonder how that turned out?

Let's go back to our good friend Dr. PAM. From the biography on his website:


Well that's odd. I thought the paper said there were no conflicts of interest. Let's look further:


"cardiovascular complications of both the viral infection and the injuries developing after the COVID-19 vaccine" sure does sound like someone who might have a financial stake in promoting the theory that vaccines cause bodily harm, doesn't it? I mean, probably not to a fruitcake like you, but to most people that might be considered a big ole' red flag.

Now let's go back to the study to look at the other jackoff doing the data collation:


Nicolas Hulscher​

Corresponding Author
Affiliation: University of Michigan School of Public Health, Ann Arbor, MI. McCullough Foundation, Dallas, TX

Email: nichulscher@gmail.com

Wait, this seems odd. He works at the McCullough Foundation, Dallas, TX with the world famous PAM??? That seems like a bit of a conflict but let's, once again, let that slide. I can't seem to find the esteemed researcher Mr. Hulscher on the website faculty. Upon searching, I saw this about half way down on the home page:

View attachment 49235

Intern Nic Hulscher??? (That's him on the right in the picture by the way. A real paragon of scientifc inquiry judging by the looks of him.) Surely the esteemed researcher Mr. Hulscher can't be one in the same as a lowly intern can it? I wonder what kind of other work he's doing. Let's "continue reading"


Another Ruh-Roh situation brewing here. Let's read on shall we?



I have to be honest, it sure seems like the good Dr. PAM and trusty sidekick Nic aren't the best sources for accurate investigation into these particular issues. We have a public health professional on the forum. Dropbear Dropbear what's your take on the validity of said study given its authors and their intent? Of course, he's likely another person of average intelligence and education who lacks Machiavellian guile, so who knows if he can be trusted!
Thank you for taking the time to answer my question, I seriously appreciate the effort. I've actually read everything you wrote, some parts multiple times, and if I'm not mistaken, only your first two statements address the "study" I posted? Unfortunately, those two statements don't really help me. No, I don't see "holes" in the methodology, I think that's by and large how you do meta-studies? You can question the usefulness of such studies etc. pp. but if that is what you are implying, just say so? Otherwise apologies for my stupidity, please elaborate on the "holes" you see. I also don't really understand how "just two authors sorting the data" is a problem? I am also not sure the part after the , is a grammatically correct sentence, at least I don't understand what you are trying to say. I am sorry. In any case it seems you have an issue with one of those two authors, which I don't care at all about, that is entirely your problem. Please try and critique the issue and not the person, that is a lot more sciency than what your are doing (which is nevertheless very funny! he does produce some ugly charts and if it looks like shit, it probably is!)
 
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oh noes another conspiracy theory promoted by the government
see you're doing it again. you can't just look at the source you have to look at who's providing the information:



Putting that aside, lets look at some of the info within this "report"

OPERATION WARP SPEED: President-elect Trump’s Operation Warp Speed — which encouraged the rapid development and authorization of the COVID-19 vaccine — was highly successful and helped save millions of lives.

COVID-19 VACCINE: Contrary to what was promised, the COVID-19 vaccine did not stop the spread or transmission of the virus.

RUSHED COVID-19 VACCINE APPROVAL: The FDA rushed approval of the COVID-19 vaccine in order to meet the Biden Administration’s arbitrary mandate timeline. Two leading FDA scientists warned their colleagues about the dangers of rushing the vaccine approval process and the likelihood of adverse events. They were ignored, and days later, the Biden Administration mandated the vaccine.

WORLD HEALTH ORGANIZATION (WHO): The WHO’s response to the COVID-19 pandemic was an abject failure because it caved to pressure from the Chinese Communist Party and placed China’s political interests ahead of its international duties. Further, the WHO’s newest effort to solve the problems exacerbated by the COVID-19 pandemic — via a “Pandemic Treaty” — may harm the United States.

SOCIAL DISTANCING: The “6 feet apart” social distancing recommendation — which shut down schools and small business across the country — was arbitrary and not based on science. During closed door testimony, Dr. Fauci testified that the guidance, “sort of just appeared.”

MASK MANDATES: There was no conclusive evidence that masks effectively protected Americans from COVID-19. Public health officials flipped-flopped on the efficacy of masks without providing Americans scientific data — causing a massive uptick in public distrust.

LOCKDOWNS: Prolonged lockdowns caused immeasurable harm to not only the American economy, but also to the mental and physical health of Americans, with a particularly negative effect on younger citizens. Rather than prioritizing the protection of the most vulnerable populations, federal and state government policies forced millions of Americans to forgo crucial elements of a healthy and financially sound life.

NEW YORK PANDEMIC FAILURES: Former New York Governor Andrew Cuomo’s March 25 Order — which forced nursing homes to accept COVID-19 positive patients — was medical malpractice. Evidence shows that Mr. Cuomo and his Administration worked to cover up the tragic aftermath of their policy decisions in an apparent effort to shield themselves from accountability.

Evidence suggests Mr. Cuomo knowingly and willfully made false statements to the Select Subcommittee on numerous occasions about material aspects of New York’s COVID-19 nursing home disaster and the ensuing cover-up. The Select Subcommittee referred Mr. Cuomo to the DOJ for criminal prosecution.TRAVEL RESTRICTIONS: President Trump’s rapidly implemented travel restrictions saved lives. During Dr. Fauci’s transcribed interview, he unequivocally agreed with every travel restriction issued by the Trump Administration. This testimony runs counter to the public narrative that the Trump Administration’s travel restrictions were xenophobic.

COVID-19 MISINFORMATION: Public health officials often spread misinformation through conflicting messaging, kneejerk reactions, and a lack of transparency. In the most egregious examples of pervasive misinformation campaigns, off-label drug use and the lab leak theory were unjustly demonized by the federal government.
 
I have no idea who those people are, nor do I care. The information you quote seems accurate and is confirmed by plenty of other sources, much of what you quote is bordering on truisms.
 

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