Nobody ever replied... I want to get a Glock, but a big one. Which models are the larger sizes? It's for home protection, so I want to put an intruder down with the first shot. Less shit to clean up that way, too.
Sounds like you are describing the Glock 21 full-size in .45acp. or G31 in .357Sig. There is also a 10mm, but that would be unadvisable unless you are a seasoned shooter.
For home protection, any of the caliber's Gaston Glock's Plastic Fantastic is chambered for would be fine, with correct ammo selection and shot placement.
A plastic gun?
Why 10mm un-advisable?